Features:
- Up to 15 unattended paddle dissolution tests (USP Apparatus 2) with the AT 70smart Paddle Station
- Up to 10 unattended basket dissolution tests (USP Apparatus 1) with the optional BS 60 Basket Station
- Automated media preparation and delivery from pre-made media or concentrate option with automated dilutions for up to 8 different media
- Tablet drop for a variety of tablet and capsule sizes including pellets and sinkers
- Unique vessel and system cleaning eliminates carryover from test to test
- Filter station uses a variety of market-available filters
- Hollow Shaft™ sampling system and Autocompliance™ provides reproducible results test after test
- Variety of analytical finishes available including on-line photometric analysis, off-line sample collection, on- and off-line capabilities, and direct injection into HPLC
- Optional pH monitoring, standard monitoring and virtual dilutions available
- Only system capable of media addition and complete media change methods
- Fully conforms to all USP and FIP guidelines Complete control via 21 CFR Part 11 compliant WinSOTAX Advanced Dissolution Software
Hardware configuration:
- Media selector with choice of four different test media (one is purified water).
- Deaeration system with helium. Tablet magazine for 7x10 or up to 7x15 samples.
- Filter station for conventional disposable filters consisting of various materials and multiple pore sizes. The filter station is adjusted to accommodate PALL standard syringe filters and the specially designed Premium filters. Filters of other manufacturers have to be tested for compatibility.
- On-line system with direct photometric evaluation utilizing different spectrophotometers.
- Off-line system with sample collection into a fraction collector for subsequent processing and analysis (e.g. dilution, HPLC etc.).
- Combined on-line/off-line system for both direct evaluation and/or sample collection.
SOTAX BS 60 Basket Station
The SOTAX BS 60 Basket Station is attached to the SOTAX AT 70smart and provides a flexible and fully automatic dissolution system for USP 1. The system configuration ensures that no carryover is possible as the basket transport system is separate for new and tested (wet) baskets; it uses a different path.
The SOTAX BS 60 Basket Station has the following features:
- 10 dissolution tests, each with 6 baskets in unmonitored permanent operation.
- 6 carousel magazines with helium purge feature.
- Simultaneous placing and removal of the baskets.
- Simple to clean.
- Used baskets slide into a collection container filled with water after the test.
- High level of operational security with monitoring sensors.
- Automatic lifting of the stirring unit of the AT 70smart when changing baskets.
- Very robust and reliable construction